Methods in Organic Synthesis (MOS) provides quick access to important new developments in organic synthesis. It covers such topics as new reactions and reagents, functional group changes, the introduction of chiral centers, and enzyme and biological transformations. Items are selected for inclusion in MOS only where there is detail of novel or interesting features in organic synthetic methods so that there are no routine preparations to plow through. Each MOS item includes reaction schemes, title and bibliographic details, and the items are categorised by five indexes: Author, Product, Reaction, Reactant and Reagent. Note: As of 2015, this database was discontinued and its functions merged into Synthetic Reaction Updates.