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Assignment 1
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Compound 1: Vitamin B12   CAS Registry #:68-19-9
Source (full name)   Vol. #   Page(s)   Types of information given
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Web Source   URL   Types of information given  
ChemFinder http://chemfinder.cambridgesoft.com/ CAS Reg. Number; structure; mol. formula; mol. wt.; links to other web sources.
Sigma-Aldrich online catalog http://www.sigmaaldrich.com/ CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; references to Merck, Beilstein, Fieser.
Ullman's Encyclopedia of Industrial Chemisry http://www.mrw.interscience.wiley.com/ueic/ Section in article "Vitamins", biological activity, some physical properties; chemical reactions; analysis; biosynthesis; fermentation processes for production; references ; economic aspects. Passing references in "Biotechnology" article.
Knovel Critical Tables http://www.knovel.com/knovel2/Toc.jsp?SpaceID=10093&BookID=761 CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; mp.
Properties of Organic Compounds http://www.chemnetbase.com/scripts/pocweb.exe CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; mp; references to Merck, Beilstein; IR, C-13 NMR spectral peaks.
Combined Chemical Dictionary http://www.chemnetbase.com/scripts/ccdweb.exe CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; mp; bp; density; vapor density; vapor pressure; flash point; refractive index; references to Merck, Beilstein; solubility; crystal structure; sources; uses; importance; hazard and toxicity data; catalog numbers; references for IR, NMR, UV spectra, synthesis, pharmacology.
SDBS spectra database http://www.aist.go.jp/RIODB/SDBS/menu-e.html CAS Reg. Number; structure; mol. formula; mol. wt.; mp; IR, ESR spectra.
NIST Chemistry Webbook http://webbook.nist.gov/ CAS Reg. Number; structure; synonyms; mol. formula; mol. wt.; reaction thermochemistry data; IR spectrum.
Encyclopedia of Spectroscopy and Spectrometry * http://dx.doi.org/10.1006/rwsp.2000.0000 In section: "Spectroelectrochemistry, Applications / Biological systems / Vitamin B12" experiments on determination of the redox processes in vitamin B12 using spectroelectrochemistry. Passing references in other sections.
Encyclopedia of Life Sciences http://www.els.net/ Several relevant articles, especially "Cobalamin Coenzymes and Vitamin B12", and "Vitamin B12: Disorders of Absorption and Metabolism", covering structure, typical enzymatic reactions, methods of study, and disorders resulting from deficiency or abnormal metabolism.

Compound 2: DMSO   CAS Registry #:67-68-5
Source (full name)  Vol. #  Page(s)  Types of information given
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Web Source  URL  Types of information given 
ChemFinder http://chemfinder.cambridgesoft.com/ CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; mp; bp; density; vapor density; flash point; links to other web sources.
Sigma-Aldrich online catalog http://www.sigmaaldrich.com/ CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; mp; bp; density; vapor density; vapor pressure; flash point; refractive index; references to Merck, Beilstein, Fieser, other works; links to FT-IR, FT-NMR spectra.
Kirk-Othmer Encyclopedia of Chemical Technology http://www.mrw.interscience.wiley.com/kirk/ In article "Sulfoxides", table of physical and thermodynamic properties; chemical reactivity; synthesis and manufacture; health and safety; uses; references. Passing references in other articles.
Ullman's Encyclopedia of Industrial Chemisry http://www.mrw.interscience.wiley.com/ueic/ In article "Sulfones and Sulfoxides", some physical properties; chemical reactivity; production; ; uses. Passing references in other articles.
CRC Handbook of Chemistry and Physics http://www.hbcpnetbase.com/ Lots of info. Thermodynamic, physical, electrical, solubility, etc. properties.
Knovel Critical Tables http://www.knovel.com/knovel2/Toc.jsp?SpaceID=10093&BookID=761 Heat capacity; CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; mp; bp; density; ref. index; critical properties; thermodynamic properties.
Properties of Organic Compounds http://www.chemnetbase.com/scripts/pocweb.exe CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; mp; bp; density; vapor density; vapor pressure; flash point; refractive index; references to Merck, Beilstein; solubility; thermodynamic properties; electric properties; mass, IR, Raman, UV, proton, C-13 NMR spectral peaks.
Combined Chemical Dictionary http://www.chemnetbase.com/scripts/ccdweb.exe CAS Reg. Number; synonyms; structure; mol. formula; mol. wt.; mp; bp; density; vapor density; vapor pressure; flash point; refractive index; references to Merck, Beilstein; solubility; thermodynamic properties; electric properties; sources; uses; importance; hazard and toxicity data; catalog numbers; references for IR, NMR, UV spectra, synthesis, pharmacology, hazards
SDBS spectra database http://www.aist.go.jp/RIODB/SDBS/menu-e.html CAS Reg. Number; structure; mol. formula; mol. wt.; mp; IR, proton, C-13 NMR, Raman spectra.
NIST Chemistry Webbook http://webbook.nist.gov/ CAS Reg. Number; structure; synonyms; mol. formula; mol. wt.; gas phase thermochemistry data; condensed phase thermochemistry data; phase change data; reaction thermochemistry data; Henry's Law data; gas phase ion energetics data; ion clustering data; IR, Mass Spectra; gas phase kinetics.
Current Protocols http://www.mrw2.interscience.wiley.com/cponline/tserver.dll Many references to uses as a solvent in biological research; analysis, safety and disposal information.
Organic Syntheses http://www.orgsyn.org/ Some 66 different reactions using dimethyl sulfoxide as a solvent in some step; each preparation has reaction diagrams, detailed preparations, yields, characterization data, safety data and references.

Concept 1: Organic syntheses using Grignard reagents  
Source (full name)  Vol. #  Page(s)  Types of information given
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Web Source   URL   Types of information given  
Kirk-Othmer Encyclopedia of Chemical Technology http://www.mrw.interscience.wiley.com/kirk/ In article "Grignard Reactions", general description, table of reaction products w/various reactants; preparation; industrial manufacture; analysis; health and safety; reactions and applications; references. Passing references in other articles.
Ullman's Encyclopedia of Industrial Chemisry http://www.mrw.interscience.wiley.com/ueic/ In article "Magnesium Compounds", section "Organomagnesium Compounds": brief information on preparation and uses. Passing references in other articles.
Organic Syntheses http://www.orgsyn.org/ 479 hits for some 150 different reactions using Grignard reagents in some step; each preparation has reaction diagrams, detailed preparations, yields, characterization data, safety data and references.
Current Protocols http://www.mrw2.interscience.wiley.com/cponline/tserver.dll From Current Protocols in Nucleic Acid Chemistry, Chapter 1 "Synthesis of Modified Nucleosides", use of Grignards in modifying nucleosides.

Concept 2: Chromatographic analysis of organophosphorus pesticides  
Source (full name)  Vol. #  Page(s)  Types of information given
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Web Source   URL   Types of information given  
 
 
 
 
 
 

Concept 3: Biochemistry of L-Dopa  
Source (full name)  Vol. #  Page(s)  Types of information given
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Web Source   URL   Types of information given  
 
 
 
 
 
 
Kirk-Othmer Encyclopedia of Chemical Technology http://www.mrw.interscience.wiley.com/kirk/ In article "Neuroregulators", L-dopa as intermediate between tyrosine and dopamine.
Current Protocols http://www.mrw2.interscience.wiley.com/cponline/tserver.dll From Current Protocols in Neuroscience, Section 9.4 "Preclinical Models of Parkinson's Disease", studies using L-dopa, and substituted L-dopa's
Encyclopedia of Life Sciences http://www.els.net/ Several relevant articles, including "Dopamine", "Neurotransmitters", and "Parkinson's Disease", covering biosynthesis and use in treating Parkinson's disease.
This page created by Chuck Huber (huber@library.ucsb.edu).
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